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Arteries are a critical part of your circulatory system, transporting blood and oxygen from the heart to the rest of the body. As you age, a variety of substances collectively referred to as plaque — including fats, cholesterol, and calcium — may accumulate in these blood vessels. A condition called atherosclerosis occurs when the buildup of plaque causes the arteries to narrow and obstructs overall blood flow throughout the body. It is a leading factor in the development of coronary artery disease, the most common type of heart disease.

Atherosclerosis, Explained

Many of the key risk factors of atherosclerosis can be managed, and there are effective treatment options that can prevent the condition from worsening. Here’s what to know about causes, symptoms, treatment, and prevention.

Atherosclerosis involves slow, progressive changes to the structure of your blood vessels. These changes typically intensify with age. As plaque accumulates, the walls of your arteries become thicker. This gradually narrows the channel within the artery through which blood flows, reducing the amount of oxygen and other nutrients that the rest of your body receives. In some cases, pieces of plaque can break off into the bloodstream and lead to the development of a blood clot.

There are arteries in nearly every part of the body, and three main types of arteries: elastic arteries, muscular arteries, and arterioles.

Elastic arteries come out of the heart and contain more elastic tissue than other types of arteries. Their flexibility allows them to receive blood at high pressure. Examples include the pulmonary artery and aorta.

Muscular arteries have less elastic tissue and more smooth muscle fiber, which allows them to expand and contract to control the flow of blood. Examples include the coronary and femoral arteries.

Arterioles are smaller vessels that branch out from the arteries and help distribute blood into microscopic capillaries.

Atherosclerosis is not limited to a certain area or type of artery. Plaque may develop in arteries in the heart, brain, pelvis, legs, arms, or kidneys. The type of artery affected in atherosclerosis can impact an individual’s symptoms, along with their risk for related health complications.

Different health conditions may arise depending on where plaque accumulates.

Coronary artery disease occurs when plaque accumulates in the arteries in or leading to the heart.

Angina, a type of chest pain, can also arise from plaque accumulation in the coronary arteries. It results from decreased blood flow to the heart muscle.

Carotid artery disease occurs when plaque accumulates in the neck arteries that deliver oxygen-rich blood to the brain.

Peripheral artery disease (PAD) occurs when plaque accumulates in the arteries in the arms and legs.

Kidney disease occurs when plaque accumulates in the renal arteries, which transport oxygen-rich blood to your kidneys.

In addition to the conditions above, extensive plaque accumulation can lead to other health complications, including heart failure, a heart attack, an abnormal heart rhythm, a stroke, and an aneurysm. Treatment can help slow the progression of atherosclerosis and prevent more serious complications.

Many factors play a role in the development of atherosclerosis, including the following.

Atherosclerosis is among the more common aging-related health issues. Your heart and blood vessels have to work harder as you age. These changes can stiffen the arteries, which makes it easier for plaque to accumulate in them.

Cholesterol is a waxy, fat-like substance that’s produced naturally by the liver and also found in certain foods. It isn’t inherently bad — your body needs a certain amount of cholesterol to produce cell membranes, hormones, and nutrients. However, high levels of low-density lipoprotein (LDL) cholesterol (“bad” cholesterol) can accumulate in the walls of your arteries and turn into plaque, factoring into a person’s risk for heart disease and stroke. (Conversely, a healthy level of high-density lipoprotein (HDL) cholesterol can potentially lower your risk for heart disease.)

Smoking damages your blood vessels and accelerates the buildup of plaque. It is a leading risk factor for peripheral artery disease. 80% of those with PAD are current or former smokers. Smoking is also associated with plaque accumulation in the aorta — the main artery of the body —  and in the coronary arteries.

High blood pressure strains and damages your coronary arteries, causing them to gradually narrow as plaque accumulates.

You may have a greater risk for atherosclerosis if you have diabetes or a family history of atherosclerosis. Physical inactivity and obesity also play a role.

Atherosclerosis symptoms typically do not appear until an artery has become severely narrow or clogged, to the point where blood flow is affected. There often aren’t noticeable symptoms of mild atherosclerosis. Symptoms of moderate to severe cases vary by the affected artery.

Atherosclerosis in coronary arteries: chest pain or pressure

Atherosclerosis in the arteries leading to your brain: sudden numbness or weakness in arms or legs, difficulty speaking, confusion, or drooping facial muscles

Atherosclerosis in the arteries in your arms and legs: pain in your legs while walking or decreased pressure the affected limb

Atherosclerosis in the arteries leading to your kidneys: high blood pressure or weakened kidney function

If you have any concerns about potential symptoms of atherosclerosis, contact your doctor as soon as possible for an evaluation.

Atherosclerosis cannot be reversed, but it is treatable. A heart-healthy lifestyle and medications can help slow the accumulation of plaque and prevent the condition from worsening.

Lifestyle changes such as quitting smoking, planning a heart-healthy diet, and exercising more frequently are often a first step in treating mild atherosclerosis. The American Heart Association suggests aiming for about 150 minutes a week of moderate-intensity aerobic activity. Building these healthy habits early on can also help prevent atherosclerosis from developing to begin with.

Your doctor may also recommend medications to prevent atherosclerosis from progressing further. The following medications are commonly used to treat atherosclerosis.

Statins such as atorvastatin and simvastatin act on the liver to prevent LDL cholesterol from forming and limit the overall amount of cholesterol circulating in your bloodstream.

Fibrates such as fenofibrate and gemfibrozil can raise HDL cholesterol and lower LDL cholesterol.

Niacin is a B vitamin that reduces the liver’s production of blood fats and can lower LDL cholesterol.

For more on cholesterol-lowering medications, read How to Manage High Cholesterol: Diet, Medications, and More.

Beta blockers such as metoprolol and carvedilol cause the heart to beat more slowly and less forcefully, lowering your blood pressure.

Calcium channel blockers such as amlodipine and diltiazem prevent calcium from entering the smooth muscle cells of the heart and blood vessels, which opens up narrowed blood vessels and lowers blood pressure.

ACE inhibitors such as lisinopril and benazepril block production of a hormone called angiotensin II, which causes blood vessels to narrow. This helps constricted blood vessels expand so that more blood can flow through.

Angiotensin II receptor blockers (ARBs) such as losartan and valsartan function similarly to ACE inhibitors and protect blood vessels from angiotensin II.

For more on blood pressure medications, read Common Types of Blood Pressure Medications.

Antiplatelet medications such as aspirin and clopidogrel may be prescribed to reduce your risk of blood clots.

Surgery may be necessary to treat severe cases of atherosclerosis, or if there is risk of serious damage to your muscle or skin tissue.

At Alto, we make it as simple as possible to manage your risk for chronic health conditions and to stay on top of your cholesterol-lowering or blood pressure medications. We will work with your doctor, your insurance (if applicable), and any third party savings programs that you may qualify for to ensure your medications are as affordable as possible. And our team of pharmacists is available to chat whenever questions come up about side effects or how to take your medication properly.

Reach out any time via phone at 1-800-874-5881, or in-app messaging.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition.

Your heart’s ability to pump oxygen-rich blood throughout the body depends on the functioning of many different structural components. The heart’s four valves allow blood to flow through your heart in the right direction. When they don’t open or close properly, the flow of blood throughout your body is disrupted.

Understanding Heart Valve Disease

Heart valve disease refers to several conditions in which one or more of your heart valves doesn’t function properly. Without treatment, heart valve disease can potentially lead to other heart health issues, but it can be managed with heart medications, lifestyle changes, and, in more severe cases, surgical procedures. Here’s what to know about recognizing and treating heart valve disease.

Your heart has four chambers: the two upper chambers, or atria, which receive blood, and the two lower chambers, or ventricles, which pump blood. Each time blood leaves or enters one of these chambers, it passes through one of the heart’s four valves:

The mitral valve, located between the left atrium and left ventricle

The tricuspid valve, located between the right atrium and right ventricle

The aortic valve, located between the left ventricle and the aorta, the heart’s main artery to the body

The pulmonic valve, located between the right ventricle and pulmonary artery, which transports blood without oxygen from the heart to the lungs

Each valve has flaps that open and close with every heartbeat. The tricuspid, aortic, and pulmonary valves all have three flaps, and the mitral valve has two. Heart valve disease occurs when one or more of the valves doesn’t open or close, affecting blood flow. These conditions typically develop from one of two main issues with heart valves: regurgitation and stenosis.

Regurgitation refers to leakage of a heart valve. When a heart valve doesn’t shut completely, blood flows backwards. This reduces forward blood flow, causing the heart to fill with too much blood.

Stenosis refers to the narrowing of a heart valve, which constrains blood flow out of the ventricles. This causes the heart to pump blood more forcefully in order to get blood to pass through the stiff, or stenotic, valve.

Regurgitation and stenosis are not mutually exclusive; one valve can develop both issues at the same time. An individual with a heart valve disease may also have issues with more than one heart valve.

All types of heart valve disease cause the heart to work harder to pump blood. Since heart valve issues can significantly disrupt blood flow, these disorders can lead to other heart health issues without effective treatment. Heart valve disease is a contributing factor in many cases of heart failure, and it can also cause strokes, blood clots, or abnormal heart rhythms.

There are several factors involved in the development of heart disease, including the following.

A history of other heart health issues, including other types of heart disease or a history of one or more heart attacks

A history of other health conditions linked to heart valve problems, including infective endocarditis and rheumatic fever

Heart disease risk factors such as high blood pressure, high cholesterol, and diabetes

Aging may also play a role in the development of heart valve disease, as the heart valves — particularly the mitral valve — can degenerate slowly over time. In addition, aging can cause calcium to accumulate on the heart valves, most commonly the aortic valve, leading to aortic stenosis.

Some types of heart valve conditions are the result of congenital heart defects, meaning they are present at birth, including the following:

The severity of heart valve disease can vary significantly by individual. Some individuals may live with a heart valve condition for many years before experiencing any symptoms, and more mild cases may never cause any symptoms at all. When symptoms of heart valve disease are present, they often include the following.

An irregular heartbeat and/or heart palpitations

Low or high blood pressure, depending on the specific heart valve condition

Treatment of heart valve disease varies by individual, as there are many types of heart valve conditions and a wide spectrum of severity.

Some mild to moderate cases of heart valve disease may not initially require treatment; your doctor may want to observe the heart valve issue for a period of time. Other cases of mild to moderate symptoms may be successfully managed with medications. Medications commonly used to relieve symptoms of heart valve disease include:

Heart rate controlling medications such as beta blockers, calcium channel blockers, and digoxin (Digox®, Lanoxin®, and Digitek®)

Blood pressure medications such as diuretics — which lower blood pressure by removing excess sodium and water — and vasodilators, which relax the muscles in the walls of blood vessels to improve blood flow

Some individuals with a heart valve condition may need surgery. There are different types of procedures that may be used, including heart valve repair surgery or heart valve replacement surgery. Sometimes a less invasive procedure called a balloon valvuloplasty is used for various types of heart valve stenosis.

The importance of a heart-healthy lifestyle

Not all types of heart valve issues are preventable, but some are. By managing your heart disease risk factors, you can lower your risk for heart health issues later in life, including heart valve disease.

Regular exercise can help you maintain healthy blood pressure, cholesterol, and blood sugar levels. The American Heart Association suggests aiming for about 150 minutes a week of moderate-intensity aerobic activity.

As you plan a heart-healthy diet, load up on foods that are low in saturated fats and trans fats. The AHA also recommends capping your sodium intake at 1,500 mg/day, as high sodium levels can raise your blood pressure. In general, processed or prepackaged foods like soups, cold cuts, bread, and frozen meals are high in sodium.

Read our previous blog, How to Prevent Heart Disease at Any Age, to learn about important heart disease prevention actions for your age group.

At Alto, we make it as simple as possible to manage your risk for heart health issues and follow the treatment plan your doctor recommends. We will work with your doctor, your insurance (if applicable), and any third party savings programs that you may qualify for to ensure your medications are as affordable as possible. And our team of pharmacists is available to chat whenever questions come up about side effects or how to take your medication properly.

Reach out any time through in-app messaging or by phone at 1-800-874-5881.

All third party trademarks (including logos and icons) referenced by Alto Pharmacy remain the property of their respective owners. Unless specifically identified as such, Alto’s use of third party trademarks does not indicate any relationship, sponsorship or endorsement between Alto and the owners of these trademarks.

Traveling with any type of medication requires advanced planning. For those with diabetes, it’s even more imperative to prepare, as there are additional factors to consider like insulin temperature control and TSA screening of diabetes supplies and equipment. Use the suggestions below to make sure you have everything you need to manage your diabetes while away from home.
Consulting your doctor

Traveling With Diabetes: How to Prepare

Traveling with any type of medication requires advanced planning. For those with diabetes, it’s even more imperative to prepare, as there are additional factors to consider like insulin temperature control and TSA screening of diabetes supplies and equipment. Use the suggestions below to make sure you have everything you need to manage your diabetes while away from home.

Schedule an appointment with your diabetes care provider before your trip to make a plan for diabetes management during your travels. Be sure to cover the following:

How will planned activities impact your care needs?

What is the recommended frequency of blood sugar monitoring?

How might changing time zones impact the timing of your insulin dosage? 

Are there any recommended vaccines for your trip?

Keep in mind that eating and physical activity levels can shift during travel — sometimes unexpectedly — so it’s important to prepare for changes in your blood glucose levels.

Travel doesn’t always go as planned, so it’s important to have extra diabetes supplies and medication on hand. A good rule of thumb is to pack twice as many supplies as you think you’ll need and to bring additional paper prescriptions for insulin or other diabetes medications.

If traveling internationally, be mindful that prescription laws vary by country. It’s a good idea to contact the U.S. embassy of the country you’re visiting for more details. Some countries may only allow a 30-day supply for certain medications and/or require you to carry an official prescription or additional information from your doctor with you.

In addition, keep your health insurance card on you throughout the duration of your travels, and review your policy for travel-related details, including whether your destination is included in your provider network.

Here’s a list of potential diabetes medications and supplies to pack. Depending on your diabetes treatment plan, some may not be relevant for you. If you’re unsure what to bring — or how much to bring — ask your diabetes care team.

Enough insulin and syringes for your trip, plus extra

Enough oral medications for your trip, plus extra

Sources of glucose to restore blood glucose levels in the event of low blood sugar, or hypoglycemia, such as over-the-counter glucose tablets (Lift Glucose Chews, TRUEplus® Glucose Tablets, ReliOn™ Glucose Tablets), over-the-counter glucose gel (Dex4® Glucose Gel, Glutose™ 15/Glutose™ 45, Insta-Glucose®), or carbohydrate-rich snacks like dried fruits, trail mix, honey, or granola bars

For a detailed list of diabetes management essentials, read How to Prepare a Diabetes Emergency Kit.

If you are traveling on a longer flight with meal service, contact your airline and ask if it’s possible to request a meal tailored to your dietary needs, with low sugar, fat, and cholesterol values. Be sure to have other food on hand in case there are any issues with your meal.

Make sure others know that you have diabetes. If traveling with others, inform them of what to do in the event of a hypoglycemia emergency. If traveling alone, have a medical ID bracelet or another form of identification that communicates your diabetes diagnosis. You should also carry a list of your current medications and doses and provider contact information.

It’s always best to pack important medications in your carry-on rather than in a checked bag. Since you’ll be bringing additional supplies and medications as a back-up, make sure at least half of them are in your carry-on.

While the U.S. Transportation Security Administration (TSA)’s current limit on liquids, gels, and creams in a carry-on bag is 3.4 ounces (100 milliliters), there are exceptions for diabetes supplies and medications. Give yourself extra time to allow for additional screening of these items. If you use a diabetes device attached to your body, such as an insulin pump or glucose monitor, it will likely require additional screening as well.

Here are some tips that may help you get through security as efficiently as possible.

Inform the TSA officer that you are carrying more than 3.4 ounces of liquid medication before your screening process begins, if applicable.

Consider printing a TSA notification card describing your condition to hand to the TSA officer.

Bring a copy of your prescription(s) with you.

Keep all medications and supplies in their original packaging.

Put your medications and supplies in a separate, clear bag, as they will need to be separated from the rest of your belongings.

If you take insulin, make sure you have what you need to keep it refrigerated. Keep in mind that insulin should not be held at extreme temperatures and storing it in an ice pack can make it unusable. Many people with diabetes use insulated medication bags to hold insulin at an appropriate temperature when traveling.

Read Taking Care of Your Insulin to learn more about safe insulin storage.

It’s important to stay proactive about your diabetes management. There may be times when you have to check your blood sugar even more frequently, for example, if you are more active than usual, and adjust your meal plans accordingly. Keep in mind that hot weather can also impact your body’s insulin use and your blood sugar levels.

Continue to hold insulin at an appropriate temperature during your travels and avoid leaving it in a hot car — including the glove compartment or trunk — or anywhere with direct sunlight. The same applies to other diabetes supplies like your blood sugar monitor and insulin pump.

If you are going on a longer trip, with a full itinerary, try to take it easy for the first few days as your body adjusts. Remember to bring snacks with you on busy days with long activities.

A diabetes pharmacy partner you can rely on

At Alto, we make it as easy as possible to manage your diabetes when traveling. We offer free, same-day delivery of medication and supplies right to your doorstep, and our dedicated diabetes team is here to answer any questions you may have before your trip.

Reach out any time via in-app secure messaging or phone at 1-800-874-5881.

Cardiomyopathy refers to a variety of diseases of the heart muscle that affect the heart’s ability to carry out its pumping function. It is a progressive condition that can lead to other heart health issues including heart failure, but it can be managed through a combination of medications, lifestyle changes, surgical procedures, and other types of treatment. Here’s what to know about causes, symptoms, and treatment options for the main types of cardiomyopathy.

Cardiomyopathy, Explained

Cardiomyopathy can be either acquired or inherited. While not all cases of cardiomyopathy have known causes, the following health factors or conditions have been linked to certain forms of cardiomyopathy.

A family health history of cardiomyopathy, heart failure, or sudden cardiac arrest

Coronary artery disease or a history of a heart attack

Endocrine diseases including type 1 and type 2 diabetes and thyroid disorders

Diseases that weaken muscle tissue such as muscular dystrophy 

Cardiomyopathy symptoms vary by individual, and by the specific type of cardiomyopathy. The following signs often become more apparent as the condition progresses.

Difficulty breathing or shortness of breath, even while at rest

An irregular heartbeat, heart murmur, or heart palpitations

Dizziness, lightheadedness, fainting, or briefly passing out

The most common type of cardiomyopathy and a leading cause for heart transplants, dilated cardiomyopathy occurs when the left ventricle — one of the heart’s main pumping chambers — becomes enlarged and cannot pump blood to other organs as effectively as a healthy heart. It can affect individuals of all ages but is most common during middle age. Men are more likely than women to develop dilated cardiomyopathy. Coronary artery disease and heart attacks are common causes, but the condition may also stem from genetics. Those with dilated cardiomyopathy may face a greater risk for heart failure in the long term.

One of the most common forms of genetic heart disease, hypertrophic cardiomyopathy is an inherited condition characterized by thickening of the heart muscle, often in the left ventricle. It affects individuals of all ages but often develops during childhood or early adulthood. There is a strong genetic component to this condition, and most affected individuals have a family history of hypertrophic cardiomyopathy. If you have a family history of hypertrophic cardiomyopathy, you may want to consult with your physician about genetic testing options. Some individuals with hypertrophic cardiomyopathy develop an arrhythmia, which is an irregular heartbeat.

The least common of the three main types of cardiomyopathy, restrictive cardiomyopathy occurs when the heart muscle stiffens and cannot fill with enough blood between heartbeats. It is most common in older age groups and often occurs as the result of another heart-related health condition such as amyloidosis, hemochromatosis, scleroderma, or sarcoidosis. Restrictive cardiomyopathy itself is not believed to be inherited, but many of the related conditions mentioned above have a genetic component.

Arrhythmogenic right ventricular dysplasia

Arrhythmogenic right ventricular dysplasia occurs when muscle in the right ventricle is replaced by fat or scar tissue, potentially leading to heart rhythm issues. It is a rare form of cardiomyopathy that often develops as the result of a genetic mutation and most commonly affects teens and young adults.

Cardiomyopathy treatment varies by individual. Your doctor may recommend a combination of medications, medical devices, or surgical procedures to control your cardiomyopathy symptoms and slow the progression of the condition.

Medications may be used to improve blood flow and the heart’s pumping function, lower blood pressure, slow your heart rate, and/or prevent blood clots. The following types of medications are commonly used in the treatment of cardiomyopathy.

Blood pressure medications such as ACE inhibitors, angiotensin II receptor blockers (ARBs), and diuretics

Blood thinners and antiplatelet medications such as warfarin (Coumadin®) and novel oral anticoagulants (NOACs)

Antiarrhythmic medications such as amiodarone (Pacerone®) and dronedarone (Multaq®)

If you are experiencing an arrhythmia as the result of cardiomyopathy, your doctor may recommend a device such as a pacemaker or an implantable cardioverter defibrillator (ICD) to help control your heartbeat. Other devices including a cardiac resynchronization therapy (CRT) device and a left ventricular assist device (LVAD) may be used to improve the heart’s pumping function and control blood flow.

Some individuals with cardiomyopathy need a non-surgical procedure to treat their condition or a related arrhythmia. Common procedures include a septal ablation, in which a portion of the thickened heart muscle is destroyed to allow for more blood flow, and a radiofrequency ablation, which targets a portion of abnormal heart tissue to address an abnormal heart rhythm. In more severe cases, open-heart surgery or a heart transplant may be required.

Maintaining a heart-healthy lifestyle is another aspect of managing cardiomyopathy, as lifestyle choices can affect the progression of the condition and the severity of symptoms. If you have cardiomyopathy, your doctor may recommend that you quit smoking (if applicable), limit your alcohol intake, plan a heart-healthy diet, and exercise more frequently. While inherited forms of cardiomyopathy cannot be prevented, these healthy habits can lower your risk for related health complications and help you experience an active life.

Reach out any time via phone at 1-800-874-5881 or in-app messaging.

A healthy immune system offers protection against the bacteria and viruses that cause illness, deploying antibodies that attack these invaders. An autoimmune disease occurs when the immune system cannot differentiate between outside germs and healthy cells and mistakenly attacks various tissues and organs throughout the body.

What is an autoimmune disease?

A healthy immune system offers protection against the bacteria and viruses that cause illness, deploying antibodies that attack these invaders. An autoimmune disease occurs when the immune system cannot differentiate between germs and the body’s own cells and mistakenly attacks various tissues and organs.

There are more than 80 of these conditions, with variation in the affected area of the body; some of the most common autoimmune disorders involve the joints and muscles, digestive tract, nervous system, and skin. There is also significant variation in day-to-day life with autoimmune disorders. Some, like type 1 diabetes, require daily management, while others may have periods of intensified symptoms known as flare-ups. In all cases, there are treatment options that can reduce discomfort and help you experience a better quality of life. Here’s what to know about the most common types of autoimmune disorders.

Causes and symptoms of autoimmune disorders

Many autoimmune disorders do not have a specific known trigger, but the following factors may play a role in the development of certain conditions.

Genetics — some autoimmune disorders such as lupus and multiple sclerosis run in families and likely have a genetic component.

Sex — of the 23.5 million Americans living with an autoimmune disease, 78% are women. Specific autoimmune disorders that are more common in women than men include rheumatoid arthritis, psoriasis, celiac disease, inflammatory bowel disease, lupus and multiple sclerosis, among others.

Obesity — being overweight or obese may increase an individual’s risk of developing rheumatoid arthritis or psoriatic arthritis.

Smoking — research suggests a connection between cigarette smoking and lupus, rheumatoid arthritis, hyperthyroidism, and multiple sclerosis.

Medications — some medications including blood pressure medications, statins (which are commonly used to treat high cholesterol), and antibiotics may increase a person’s risk for certain autoimmune disorders. Consult with your doctor about medication side effects if you have concerns.

While exact symptoms and treatment options vary by condition, as explained in more detail below, there is also some overlap. Fatigue, joint pain and swelling, rashes and other skin issues, digestive issues, and swollen glands are common signs of a variety of autoimmune disorders.

Most autoimmune disorders do not have one single test to confirm or rule out a diagnosis. With the majority of these conditions, the diagnosis process involves several steps including a physical exam and multiple tests.

If you have potential symptoms of an autoimmune disease, a common first step is an antinuclear antibody (ANA) test. This is a blood test that checks for antinuclear antibodies, the type of antibodies that attack healthy cells. If you have a positive ANA result, your doctor will likely recommend additional tests to identify the specific autoimmune disease.

A negative ANA test does not necessarily mean that you do not have an autoimmune disease. If you have negative ANA results, your doctor may recommend additional tests for other antibodies or inflammation markers depending on your symptoms. Tests used to diagnose autoimmune disorders include:

An erythrocyte sedimentation rate (ESR) test — which examines how quickly your red blood cells sink to the bottom of a test tube — may be used to diagnose rheumatoid arthritis and lupus. Higher rates of settlement may indicate inflammation.

A c-reactive protein (CRP) test — which identifies your blood levels of CRP, an inflammation-linked protein produced in your liver — may be used to diagnose rheumatoid arthritis, lupus, and inflammatory bowel disease.

A rheumatoid factor (RF) test checks for rheumatoid factor, an antibody found in about 80% of individuals with rheumatoid arthritis.

Depending on your symptoms, your healthcare provider may refer you to one of the following specialists:

A rheumatologist who treats autoimmune disorders of the joints and muscles including rheumatoid arthritis and lupus.

A gastroenterologist who treats autoimmune disorders of the digestive system including Crohn’s disease, celiac disease, and ulcerative colitis.

An endocrinologist who treats autoimmune disorders of the endocrine system including Graves’ disease and Hashimoto’s thyroiditis.

A dermatologist who treats skin-related autoimmune disorders including psoriasis.

Common autoimmune disorders and treatment

These are some of the most common types of autoimmune disorders affecting individuals in the U.S. Symptoms, treatment, and diagnostic tests vary by condition.

Rheumatoid arthritis occurs when your immune system attacks the lining of your joints, causing pain and inflammation throughout your body. It is a progressive condition, and getting an early diagnosis and staying proactive about treatment can help prevent more severe damage to your joints.

Several medications may be used to reduce the pain and inflammation caused by rheumatoid arthritis, including over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil®), aspirin (Bayer®) or naproxen (Aleve®); acetaminophen (Tylenol®); and Janus kinase (JAK) inhibitors such as baricitinib (Olumiant®), tofacitinib (Xeljanz®), and upadacitinib (Rinvoq®). In addition, avoiding or reducing your intake of sugars and refined carbohydrates and gluten can also help reduce inflammation.

Disease-modifying anti-rheumatic drugs (DMARDs) like methotrexate (Rheumatrex®), sulfasalazine (Azulfidine®), and leflunomide (Arava®) and injectable biologic DMARDs like etanercept (Enbrel®), infliximab (Remicade®), adalimumab (Humira®), and certolizumab pegol (Cimzia®) are often prescribed to slow tissue damage.

Type 1 diabetes is an autoimmune condition that occurs when the body mistakenly attacks the pancreas with antibodies. This destroys the pancreas’s insulin-producing cells, so individuals with type 1 diabetes cannot produce any insulin and rely on daily insulin therapy to manage their blood sugar.

For more information on managing type 1 diabetes, read our previous blogs:

What’s the Difference between Type 1 and Type 2 Diabetes?

How to Live with Type 1 Diabetes at Any Age

Psoriasis is a skin disorder that occurs when inflammation caused by an immune response causes new skin cells to grow too quickly. It is characterized by thick patches of skin covered with white or silver scales, also referred to as plaques. There is a genetic component, and psoriasis often runs in families. 

Many individuals with psoriasis experience periodic flare-ups. While not all psoriasis flare-ups can be attributed to a specific cause, skin injury, stress, and cold weather are common triggers.

There are a variety of treatments for psoriasis, including steroid creams; anthralin (Drithocreme HP® and Zithranol®), an anti-inflammatory medication; moisturizers; UV light therapy; vitamin D3 ointment; and vitamin A creams.

Systemic lupus erythematosus (SLE), the most common type of lupus, affects many different parts of the body including the skin, joints, kidneys, brain, and heart. Common symptoms include joint pain and swelling, severe fatigue, and rashes. Without effective treatment, lupus can lead to other health complications over time, including blood clots and inflammation of the heart or kidneys, and increase your risk for a heart attack or stroke. Getting diagnosed early and starting treatment as soon as possible is critical to managing lupus.

Lupus treatment varies depending on the severity of symptoms and which part of the body is affected. Other-the-counter NSAIDs and oral corticosteroids including prednisone (Deltasone®, Prednicot®) may be used to treat joint pain and stiffness. Antimalarial medications including hydroxychloroquine (Plaquenil®) are often prescribed to reduce pain and inflammation, prevent flare-ups, and treat rashes.

Inflammatory bowel disease refers to several autoimmune diseases that affect the digestive tract including Crohn’s disease, which involves any part of the small or large intestine, and ulcerative colitis, which involves the colon, rectum, or both organs.

Common symptoms of both Crohn’s disease and ulcerative colitis include diarrhea, abdominal cramps, bloody stools, fever, fatigue, loss of appetite, and weight loss. Many individuals with these conditions experience periods of time without symptoms, also known as remission. Treatment options include the following:

Antidiarrheal and anti-inflammatory medications such as oral 5-aminosalicylates and corticosteroids

Immunomodulators, a group of medications that act on the immune system to reduce the inflammation that causes Crohn’s

Biologics, a group of medications that are derived from antibodies and used to prevent inflammation in more severe cases, such as adalimumab (Humira®), golimumab (Simponi®), infliximab (Remicade®), tofacitinib (Xeljanz®), ustekinumab (Stelara®), and vedolizumab (Entyvio®)

Other common autoimmune diseases include:

Multiple sclerosis, which affects the nervous system

Addison’s disease, which affects the adrenal glands

Graves’ disease, which affects the thyroid gland in the neck

Celiac disease, which affects the digestive tract

Living with any chronic condition is easier with a reliable pharmacy partner by your side. Our pharmacists have specialized training in the treatment of autoimmune diseases and can answer any questions you may have, from medication side effects to non-pharmacological treatment options and navigating lifestyle changes. In addition, we offer free, same-day delivery and medication management tools like reminders and auto refills in our app to make it as simple as possible to stay on track with your treatment.

To learn more, reach out any time through in-app secure messaging or by phone at 1-800-874-5881.

Millions of individuals with type 1 and type 2 diabetes need insulin every day to keep their blood sugar levels in a healthy range. In recent decades, it has grown increasingly difficult for many to access this life-saving medication, as insulin prices continue to rise.

Managing the Costs of Insulin

Millions of individuals with type 1 and type 2 diabetes need insulin every day to keep their blood sugar levels in a healthy range. In recent decades, it has grown increasingly difficult for many to access this life-saving medication, as insulin prices continue to rise. Take a look at these recent statistics:

Blog

Atherosclerosis, Explained

Understanding Heart Valve Disease

Traveling With Diabetes: How to Prepare

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Managing Type 2 Diabetes at Any Age

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