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Join us in delivering our industry-leading pharmacy care to millions of people across the country. As a member of the team, you’ll play an integral role in improving our customers’ quality of life and redefining what’s possible in pharmacy. 

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Blog | Alto Pharmacy

Polycystic ovary syndrome (PCOS) is a condition that affects women of reproductive age and is characterized by a hormone imbalance. It can impact many areas of a woman’s health, including menstrual cycles, fertility, insulin levels, and risk of cardiovascular disease.

How Polycystic Ovary Syndrome (PCOS) Affects Fertility

Symptoms of PCOS can be treated through a combination of medications and lifestyle changes. Here’s what to know about the condition’s causes, symptoms, and treatment options.

Polycystic ovary syndrome has three defining symptoms: high levels of male hormones, irregular menstrual cycles, and the development of cysts in the ovaries. These features overlap.

Many women with PCOS have higher levels of androgen hormones, which are responsible for the development of certain male characteristics. For those with PCOS, overproduction of androgens leads to irregular menstrual cycles, hair loss, extra growth of hair on the face and body, and acne.

The cysts that develop in the ovaries are small follicles containing an immature egg. Since these eggs do not reach maturity, ovulation — the release of a mature egg from the ovaries — does not occur. The absence of ovulation leads to further imbalance of hormones, as progesterone decreases.

PCOS is the leading cause of female infertility.

Polycystic ovary syndrome can develop at any age after puberty. It is estimated that 5-10% of women between the ages of 15-44 have the condition.

The specific causes of PCOS have not been identified, but the medical community believes that condition is the result of several intersecting factors: insulin resistance, higher levels of androgens, higher levels of inflammation, and an irregular menstrual cycle.

Some evidence suggests that PCOS may have a genetic component. You may have a higher risk of developing PCOS if you have a mother, sister, or aunt with the condition. Obesity is also a risk factor.

Common symptoms of polycystic ovary syndrome include:

Irregular, absent, or abnormally short (i.e., less than 21 days) menstrual periods

Excess hair on the face, chin, chest, abdomen, or upper thighs, also referred to as hirsutism

Weight gain or difficulty maintaining a healthy weight

Patches of darkened skin, particularly on the neck, in the groin, and beneath the breasts

Small flaps of excess skin near the neck or armpits, sometimes referred to as skin tags

Infertility, defined as the inability to get pregnant after twelve months or more of unprotected sex

The hormone imbalances that characterize PCOS can affect many areas of a woman’s health, including the following.

Infertility is a common symptom of PCOS, as hormone levels interfere with ovulation, an important step in reproduction. However, PCOS is a highly treatable cause of infertility. Many individuals and couples affected by PCOS do become pregnant after fertility treatment.

During pregnancy, women with PCOS may face a greater risk for miscarriage, high blood pressure, and gestational diabetes. They are also more likely to deliver prematurely. If you have PCOS, you can set yourself up for a healthy pregnancy by maintaining a healthy weight and blood sugar levels before trying to conceive and during pregnancy.

Insulin is a hormone naturally produced in the pancreas. It helps convert sugar, or glucose, into energy. Type 2 diabetes occurs when blood sugar levels rise due to issues with the body’s production or use of insulin. Since insulin resistance is often a symptom of PCOS, many individuals with the condition have a greater risk for type 2 diabetes.

Individuals with PCOS are also more likely to develop metabolic syndrome, a group of conditions associated with a higher risk for diabetes and heart disease, including:

Abnormal cholesterol or triglyceride levels

Endometrial hyperplasia, a condition in which the lining of the uterus becomes too thick, is also associated with PCOS. It can increase a woman’s risk for endometrial cancer.

The process for diagnosing PCOS includes a conversation about your health history, a physical exam, and several tests that can rule out other causes of PCOS symptoms.

During the physical exam, a healthcare provider typically measures blood pressure, body mass index (BMI), and waist size. They will also check your skin for extra hair, acne, or discoloration.

Your doctor will likely conduct a pelvic exam to check for signs of high androgen levels and abnormalities with your ovaries. Then, a pelvic ultrasound, or sonogram, will check the ovaries for cysts and scan the uterine lining.

Blood tests may be used to measure levels of androgens as well as hormones linked to other health conditions with similar symptoms as PCOS. You may also be tested for high cholesterol and diabetes.

If other health conditions have been ruled out, you must have at least two of the following symptoms to be diagnosed with PCOS:

Irregular, absent, or abnormally short menstrual periods

Signs of high androgen levels such as hirsutism, acne, or thinning of hair on the scalp

PCOS and related medical conditions can be managed through a variety of treatments including medications and lifestyle changes. Treatment is tailored to an individual’s health history, PCOS symptoms, and reproductive goals. Here’s how different treatment options target various symptoms of PCOS.

Hormonal birth control, which may contain both estrogen and progestin, is often used to regulate a woman’s menstrual cycle. It can also reduce hirsutism and acne and lower the risk of endometrial cancer. Many women who do not have plans to get pregnant use hormonal birth control as a long-term treatment for PCOS.

Metformin, an oral medication most commonly used to treat type 2 diabetes, is sometimes used off-label to treat PCOS. It improves the body’s response to insulin and can lower blood sugar and androgen levels. In some cases, it may be effective at restoring ovulation, though it typically does not treat hirsutism or acne.

Anti-androgen medications such as spironolactone (CaroSpir® and Aldactone®) block the effects of androgens and treat hirsutism. They are often used in combination with birth control and should not be used during pregnancy or when trying to conceive.

Maintaining a healthy weight can help regulate menstrual cycles. It may also improve insulin levels and treat excess hair growth and acne. Additionally, following a heart-healthy diet and staying physically active is especially important for those with PCOS.

In many cases, metformin or lifestyle changes can help address ovulation issues associated with PCOS. There are additional treatments that restore ovulation in women with PCOS, including oral medications used to treat infertility such as Clomid® and Femara® and injectable fertility medications including gonadotropins.

A procedure called laparoscopic ovarian drilling is a fertility treatment typically reserved for cases when medication is not effective.

PCOS treatment looks different for each individual, and our team has the expertise to support your personal health journey. Whether you are getting started with hormonal birth control, metformin, or fertility treatment, we’re here to simplify medication management and keep you supported.

We offer free, same-day delivery seven days a week, with temperature controlled packaging that ensures fertility medications always arrive in the right condition. And we’ll work with your doctor, your insurance (if applicable), and any third party savings programs that you may qualify for to ensure your medications are as affordable as possible.

To learn more, reach out any time through secure in-app messaging or by phone at 1-800-874-5881.

This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition.

All third party trademarks (including logos and icons) referenced by Alto Pharmacy remain the property of their respective owners. Unless specifically identified as such, Alto’s use of third party trademarks does not indicate any relationship, sponsorship or endorsement between Alto and the owners of these trademarks.

About 9% of men and 11% of women in the U.S. have faced fertility issues. These challenges may feel overwhelming, but there are a variety of treatment options for both male and female infertility to support your family building journey.

Here’s an overview of the causes and symptoms of male and female infertility and common fertility treatments.

Infertility, Explained

About 9% of men and 11% of women in the U.S. have faced fertility issues. These challenges may feel overwhelming, but there are a variety of treatment options for both male and female infertility to support your family building journey.

Here’s an overview of the causes and symptoms of male and female infertility and common fertility treatments.

Infertility, defined as the inability to get pregnant after twelve months or more of unprotected sex, is a health condition that affects both men and women. Approximately one-third of infertility cases stem from a female reproductive factor, one-third stem from a male reproductive factor, and one-third stem from a combination of both or unknown causes.

These are some common causes of female infertility.

The majority of female infertility cases are caused by problems with ovulation, the release of a mature egg from the ovaries. There are several causes of ovulation disorders, including the following.

Polycystic ovary syndrome (PCOS), a condition characterized by a hormone imbalance that impacts ovulation. It is the leading cause of female infertility.

Excessive exercise, eating disorders, or stress, each of which can result in hormonal imbalances

Primary ovarian insufficiency, sometimes referred to as premature ovarian failure

Fallopian tube damage or blockage can prevent sperm from reaching an egg, or fertilized eggs from attaching to the uterus. Common causes of fallopian tube damage or blockage include pelvic inflammatory disease — an infection of the uterus and fallopian tubes from chlamydia, gonorrhea, or other sexually transmitted infections — or a prior surgery in the abdomen or pelvis, including surgery for ectopic pregnancy.

Uterine or cervical issues such as the following can disrupt the implantation of an egg into the uterus or increase a woman’s risk for miscarriage.

Benign polyps or fibroids may block fallopian tubes or interfere with the implantation of an embryo. However, many women with these growths are able to conceive.

Structural issues with the uterus that are present at birth

Cervical stenosis, a narrowing of the cervix

Endometriosis is a condition in which tissue that should only grow in the uterus implants and grows elsewhere. The abnormal tissue growth — as well as surgical procedures to remove it — can block the fallopian tubes, preventing the fertilization of an egg. In some cases, endometriosis may interfere with implantation of the fertilized egg, or embryo.

Male infertility is most often an issue of sperm production — including the quantity and quality of sperm produced — or of sperm mobility, which affects the sperm’s ability to find and fertilize an egg. A blockage in the testicle or damage to the reproductive organs can also contribute to male infertility.

Age is a factor in both male and female fertility issues. The quality and quantity of a woman’s eggs begin to decline as she enters her mid-thirties, and age factors into the success rates of in vitro fertilization (IVF).

Many individuals and couples first learn of a fertility issue after trying to conceive without success, and the primary symptom of infertility is the inability to get pregnant. There aren’t always noticeable symptoms, but the following may indicate an underlying fertility problem.

A menstrual cycle that’s irregular, absent, longer than 35 days, or less than 21 days

Unusually light or heavy bleeding during menstrual cycles

Erectile dysfunction or low sex drive in men

The timeline for seeking fertility treatment depends on your age. If you are under the age of 35, most health experts suggest consulting a reproductive specialist after a year of trying to conceive. If you are between 35 and 40, you may want to pursue testing or treatment after six months of trying to become pregnant. And if you are over 40, you may want to pursue testing or treatment before you start trying to conceive.

An evaluation for fertility issues and potential treatment begins with a conversation about your health history. Several tests may be used during the diagnostic process, including the following.

An hysterosalpingogram (HSG), an x-ray taken to examine issues within the uterus and fallopian tubes

Blood tests to measure hormone levels related to fertility and reproduction

Ovarian reserve testing, which evaluates the number of viable eggs in your ovarian reserve. These are typically used for women over 35 or those at risk of a low egg count for other reasons.

A semen test is used to diagnose most cases of male infertility. This identifies how many sperm you produce and whether the sperm are normal in shape and movement — healthy sperm have an oval head and long tail. In some cases, additional blood tests and/or genital ultrasounds may be used to rule out other health conditions.

Fertility problems do not mean that you won’t be able to have children biologically. There are many treatment options that can help increase your chances of conception. The most effective course of treatment depends on the underlying cause of your or your partner’s fertility issues. These are among the most common fertility treatments.

Forms of assisted reproductive technology (ART) including in vitro fertilization (IVF), a process in which eggs and sperm are fertilized in a laboratory and then placed into the uterus with the potential outcome of a pregnancy. In addition to treating female infertility, IVF can also be used when male infertility is a factor.

Intrauterine insemination (IUI), a type of artificial insemination in which sperm that have been washed and concentrated are placed directly into a woman’s uterus during ovulation.

Injectable fertility medications including gonadotropins and oral fertility medications such as Clomid® and Femara® can treat fertility-related hormonal imbalances.

Your doctor may also recommend lifestyle changes or treating a related health condition.

A fertility pharmacy partner you can rely on

Since 2016, Alto has supported more than 50,000 fertility journeys. We understand that fertility treatment is a significant investment — physically, emotionally, and financially — and we see ourselves as a partner in your health.

We offer free, same-day delivery seven days a week and temperature controlled packaging to ensure that your fertility medications always arrive in the right condition. And our fertility-trained pharmacists are available until 9 pm PST (12 midnight EST) on weeknights to offer any support you need.

Reach out any time via phone at 1-800-874-5881, or in-app messaging.

We are honored to announce that for the second year in a row, Alto Pharmacy has been recognized by Forbes as one of America’s Best Startup Employers. This award celebrates our commitment to employer reputation, employee satisfaction and growth.

Alto Pharmacy Announced as One of Forbes Best Startup Employers for the Second Consecutive Year!

When Alto’s founders set out to transform the pharmacy experience, they outlined a vision whereby our work could improve the quality of life for everyone who needs medicine. Through this foundation grounded in helping people, we have built a company culture centered in care, inclusion, and impact. 

We are honored to announce that for the second year in a row, Alto Pharmacy has been recognized by Forbes as one of America’s Best Startup Employers. This award celebrates our commitment to employer reputation, employee satisfaction and growth. 

This recognition follows Alto Pharmacy's recent admission as a Great Place to Work-Certified™ company – awarded based on employee feedback and a rigorous assessment of Alto’s culture and benefits. Given the impact we strive to make on the communities we serve, we are humbled to share this most recent recognition alongside other accolades over the past year, including: 

The Healthcare Technology Report: Top 100 Healthcare Technology Companies of 2021 

The Healthcare Technology Report: Top 25 Consumer HealthTech Executives of 2021

The Healthcare Technology Report: Top 25 Women Leaders in Consumer HealthTech of 2021

These recognitions and achievements are only made possible through the hard work and dedication of the entire Alto team. If you are passionate about shaping the future of pharmacy, join us as we deliver our industry-leading pharmacy care to millions of people across the country.

For the full employers list and an overview of the selection methodology, head to the Forbes site.

With more engineers contributing to Alto’s codebase than ever before, we needed to establish better boundaries: which team owns what? Here’s how we developed a tagging-based solution to code ownership and drove and measured adoption.

How We Established Better Boundaries and Clearer Code Ownership at Alto

Some problems are nice to have. Over the course of 2020 the engineering team at Alto saw explosive growth, expanding from about fifteen to more than seventy individual contributors. Growth at this pace required us to rethink our team structures and priorities more than once. This growth felt amazing: the new capacity enabled us to make progress on our backlogs like never before.

But still, there were challenges. We saw a steady rise in merge conflicts as more people contributed to the same code base. Build times increased as more and more code was contributed. A big influx of new perspectives and talent also meant new gaps in historical context and responsibility. New teams took big bites out of their new priorities — great! But what about the old ones? Who was going to fix that bug? Who needs to review this PR? Who is accountable for this performance problem?

Who, in short, owned what? By the end of 2020, it was clear to us that a good, practical, working answer to this question would be the critical first step to continuing smooth, rapid, distributed iteration on our product.

Up to this point, the large majority of product development at Alto had happened in the context of a Ruby on Rails monolith, which — over a half decade of intense development — had grown pretty large. We’d stuck more or less to the default Rails convention of organizing code by function rather than feature, which meant that our code was distributed across a few mostly flat and very broad subdirectories such as '/models' and '/controllers', making it difficult to learn much about the structure and ownership of our business domains by merely looking at how the code was laid out. We knew that this was not going to work for us over the long term.

Our long term vision started to coalesce around a notion of “better boundaries.” First, we would modularize the monolith along the lines suggested by Shopify’s packwerk utility. Then, we would carve some of those modules out into separate engines that could be built and tested separately. Finally, we’d deploy and operate some of those engines independently as their own services. Clear ownership was fundamental to this plan: on either side of an effective boundary, you need to know not just what it is but also who owns it. We lacked that clarity.

The RFC (Request for Comments) we ultimately adopted opened with four questions:

How might we produce a domain model and do something useful at the same time?

How will we avoid imposing (the wrong) prescriptive model from the top down?

How will we keep it up to date and accurate?

We considered jumping straight into moving files around into a more modular structure. Ultimately we decided against this approach as a first step for a number of reasons. The benefit of moving files around is mostly abstract — it’s not immediately clear what to do with a better module structure. It’s relatively expensive to move files around in a Rails app — doing so typically requires you to rename the contents (and update all its callers), which amounts to a lot of busy work, and it’s extra expensive to be wrong. And the in-between state is rough: which example should I follow in deciding where to put my new file? First you are obligated to create a map of the future state, and then to keep that map in sync with reality as you go.

Instead, we opted for a lightweight solution that would allow us to map our domains and their owners in the code itself — helping to ensure it’s up to date and accurate — without having to restructure it at the same time. We’d do this by tagging code in code comments, and then building tools to leverage these tags in various ways to increase visibility and enforce ownership. This has the nice effect of producing a new domain map incrementally from the bottom up, rather than prescriptively from the top down.

We called this the '@owners' tag, and it looks like this:

# @owners { team: platform, domain: orders }
class Wunderbar::OrdersController < Wunderbar::WunderbarController
  def show
		...
  end

  # @owners { team: inventory }
  def out_of_stock
    ...
  end
end

We based our tooling around extending the YARD documentation tool to recognize this as a custom tag. You can teach YARD to recognize a custom tag by passing a command line option like '--tag owners:"Owners"', which by default will cause the tag value to appear in generated documentation under the header “Owners”. The Ruby API for declaring a tag programmatically is shown in the snippet below as well.

We wanted the tag to be interpreted hierarchically to handle cases where ownership has diverged within the same class or module, such that we might want to tag one or two methods differently from the rest, as well as to ease the burden when all of the classes / modules / methods under a namespace belong to the same team and domain, since you can just tag the shared parent. We set an initial goal around getting 100% of our methods covered by at least a “team” value, at which point we would require all code to be covered in our build process.

To get a basic feel for how to work with these tags, make sure the 'yard' gem is available, tag a couple of your files, and then try running the code below in your project. It will print out the tag associated with each tagged code block.

require 'yard'
# Define the custom tag.
YARD::Tags::Library.define_tag('Owners', :owners)

# Parse your codebase. You might want to pass a more specific path here.
YARD.parse('.')

# Load all the method, class and module code blocks into memory
code_blocks = YARD::Registry.all(:method, :class, :module)

# Print the tag associated with each tagged block.
code_blocks.each do |code_block|
  tag = code_block.tag('owners')
  # automatically tag nested classes, modules and methods.
  while tag.nil? && code_block.namespace != nil && [:class, :module].include?(code_block.namespace.type)
    code_block = code_block.namespace
    tag = code_block.tag('owners')
  end
  print "Code Block: #{code_block}, tag: #{tag.text}, line: #{tag.line}" if tag
end

We ultimately developed a handful of CLI tools based on this technique that allow us to produce reports measuring the percentage of code covered by team and domain at different levels, among other things:

bin/yardowners --help
Usage: bin/yardowners [options]
        --methods                    view by methods
        --files                      view by files
        --teams                      teams report
        --domains                    domains repot
        --team=TEAM                  filter by team
        --domain=DOMAIN              filter by domain
        --codeowners                 update codeowners
        --lint                       lint owners tags
        --require-domains            lint for presence of domain in  
owners tags
    -h, --help                       display this help and exit

We use this CLI to add checks to our CI process around coverage / correctness, as well as to report progress toward our goals of 100% coverage.

To get the tagging process started across the organization, we dumped all of our class and module names (thanks again, YARD!) into a big spreadsheet, and then asked each team to get together and spend a bit of time putting their names next to the ones they owned. We adopted the attitude that it was better to have the wrong value than no value, since it would be easy to adjust later.

We covered a good 80% of the code using this spreadsheet by the time each team had taken an initial pass. From there, we filled the blanks in with “TODO”, and then wrote a little script to automatically insert the tags into the code (again based on the YARD metadata, which conveniently gives you the line numbers for the top of each class / module declaration).

At that point, we enabled a linter requiring 100% team owner coverage on all new PRs. We set a new goal to eliminate TODOs, and chipped away at it over the course of a month or so. We then repeated this process for the “domain” values, driving that to 100% as well. We found that the spreadsheet-based divide-and-conquer approach allowed us to cover a lot of ground very quickly.

Once we were able to parse our '@owners' tags, the first and most important thing we did with them was to automatically generate our CODEOWNERS file. We enforce that each tagged team maps to a team name in github and check that CODEOWNERS is up to date during the build process. This new process introduced some friction, as teams started getting tagged every time a file they were tagged on changed. This turned out to be great, because it sparked a number of very productive negotiations around ownership and scope that got hashed out in code review. We keep our CODEOWNERS file synced with Sentry, too, so that exceptions raised by files you tagged as yours get assigned to your team automatically. We also track and report on the performance of individual endpoints by team according to how they are tagged.

The new owners tag hasn’t fixed all our problems by any means, but it has proved fundamental to our ability to operate as a growing set of increasingly independent teams with well specified responsibilities. In subsequent posts, we’ll talk more about how we’re using our new domain map and a suite of other cool tools to build better boundaries within and ultimately escape from our monolith.

Interested in learning more about engineering at Alto? Follow us on LinkedIn.

Skin, the body’s largest organ, protects you against disease and infection and regulates your body temperature, among other crucial functions. It’s important to take good care of this vital and complex organ, as there are a variety of skin problems that can occur, including serious issues like skin cancer. Here’s what to know about the structure of your skin and how you can protect it.

An Introduction to Skin Health

Your skin is composed of three layers: the epidermis (top layer), the dermis (middle layer), and the hypodermis (bottom layer). Each layer has an important purpose.

The epidermis is what you see when you look at your skin. It prevents infections by blocking bacteria and germs from entering your bloodstream. There are three types of cells in the epidermis:

Squamous cells, which form the top layer of the epidermis

Basal cells, which sit beneath the squamous cells

Melanocytes, which produce melanin — the pigment that gives skin its color — and are located at the bottom of the epidermis

Skin cancer first develops in the epidermis, with the three most common types of skin cancer affecting one of the three cells above.

The dermis, the middle layer of skin, plays an important role in your overall skin health. It contains collagen, a protein that keeps skin cells strong and healthy, and blood vessels that deliver nutrients to the epidermis. In addition, its sweat glands help regulate your body temperature, its hair follicles stimulate hair growth, and its nerves allow you to experience the sensation of touch.

The bottom layer of your skin is the fattiest, cushioning your muscles and bones when you fall and protecting you from the cold or extreme heat. The dermis’ nerves and blood vessels continue in the hypodermis, where they expand and reach the rest of your body.

The sun emits a form of electromagnetic radiation called UV radiation that can damage the skin both directly and indirectly. This damage occurs gradually over time, potentially resulting in skin health issues such as:

Freckles, moles, and other benign skin growths

Skin cancer is one of the most common types of cancer in the U.S. It primarily occurs in parts of your body that receive the most sun exposure, such as your face, neck, hands, and arms, but it may develop anywhere.

Skin cancer can affect anyone, but you may be at a higher risk if you have lighter skin, a family history of skin cancer, prevalent moles, a history of severe sunburns, or a weakened immune system.

There are three common types of skin cancer: basal and squamous cell carcinomas, which develop in the epidermis’ basal and squamous cells, and melanoma, which develops in the melanocytes. Basal and squamous cell carcinomas are very treatable. Melanoma is the most serious type of skin cancer since it can spread to other organs if not detected early.

Limiting your exposure to UV rays is the most important thing you can do to prevent skin cancer and other types of skin damage. Wear a broad-spectrum sunscreen with a sun protection factor (SPF) of 15 or higher every day, even if it isn’t sunny, since up to 80% of UV rays can pass through clouds. Be extra careful around bright surfaces like snow, water, and sand, which can amplify UV exposure and increase your risk of a sunburn.

The strength of the sun’s rays fluctuates throughout each day, and from one day to the next. Avoid direct sunlight as much as possible between 10 am to 4 pm daylight savings time (9 am to 3 pm standard time), when UV radiation is at its strongest.

You are exposed to more UV radiation at higher altitudes, where more UV rays can reach the Earth’s surface. Check the UV Index for a daily forecast of local UV radiation strength on a scale of 0 to 11. Extra precautions against UV rays are recommended when the index is a three or higher. Protective clothing like long-sleeve shirts and wide-brimmed hats can help keep UV rays away from your skin.

It’s also best to avoid tanning beds, which use UV radiation and can increase your risk for skin cancer.

Unlike many other types of cancer, skin cancer is often visible. Checking your skin regularly to identify new or changing skin growths such as moles can help you detect any potential issues early on, when they will be easier to treat.

Skin cancer can take various forms. In general, if you see anything new, changing, or unusual, schedule an appointment with a dermatologist as soon as possible. Here are common signs of skin cancer to watch for, according to The Skin Cancer Foundation:

A skin growth that increases in size and appears pearly, transparent, tan, brown, black, or multicolored

A mole, birthmark, or brown spot that increases in size, thickness, changes color or texture, or is bigger than a pencil eraser

A spot or sore that continues to itch, hurt, crust, scab, or bleed

An open sore that does not heal within three weeks

You can also use the first five letters of the alphabet as a tool for recognizing melanoma warning signs in particular:

Asymmetry: Unlike a round or oval mole, melanomas tend to be asymmetrical, with one side of the growth appearing differently from the other. For example, one side may appear darker and raised while the other looks lighter and flat.

Border: The borders of melanomas are uneven, in contrast to the smoother borders of common moles.

Color: Benign moles are often just one shade of brown, but melanomas may have multiple shades of brown, tan, or black. Other colors like red, white, or blue may appear as it grows. Many health experts also consider it to be a melanoma warning sign if a skin growth is darker than others.

Diameter: While it’s best to detect melanoma before it grows, scan for any skin growth the size of a pencil eraser or larger, approximately ¼ inch in diameter.

Evolving: Changes in size, shape, color, or elevation may be a warning sign of melanoma. Watch for new symptoms like bleeding or itching as well.

Even if you don’t see anything unusual during these scans, it’s important to visit a dermatologist at least once a year for an exam as part of your overall preventative care.

At Alto, a pharmacist is your partner in health. If you take medication, we will work with your doctor, your insurance (if applicable), and any third party savings programs that you may qualify for to make your medications as affordable as possible. And our team of pharmacists is available to chat whenever questions come up. Reach out any time through in-app secure messaging or by phone at 1-800-874-5881.

October 11 marks National Coming Out Day, an opportunity to celebrate all those who have come out as LGBTQ+ and recognize the courage they’ve demonstrated by choosing to be their authentic selves.

Celebrating National Coming Out Day at Alto

October 11 marks National Coming Out Day, an opportunity to celebrate all those who have come out as LGBTQ+ and recognize the courage they’ve demonstrated by choosing to be their authentic selves. In honor of this annual celebration, we sat down with two Alto team members — Ben Romero (he/they), Business Operations Manager for Health Plans and Travis White (he/him), Senior Software Engineer — who generously shared their experiences of coming out as bisexual/queer. Here are their stories, in their own words.

Ben: Like a lot of folks, I avoided coming out for most of my life. I grew up knowing that I wasn’t exactly straight and later recognized that I’m bisexual. I remember my entire experience around my sexuality being wrapped in shame. I would reluctantly conform to heteronormativity just to avoid the fear of being outed or questioned. It wasn't until college that I first felt like I could open myself up to the experience and validation that I deserved. By the time I graduated from college, I had a refreshed sense of my place in the world, but I was still hiding my sexuality from my family.

Five years after college, I was finally ready to be open with my family about being bisexual, and it was the first time I felt as if I had to “come out.” At the time I was engaged to my non-binary/queer partner. My family knew my partner as a woman, but my partner was also beginning to validate their nonbinary gender experience. All I could think about was how much of a disservice it would be to our identities as a queer couple if we started our marriage having to assume more invalidating heteronormative assumptions. I first told my closest family members — my younger brother and parents — who supported me unconditionally and showed me so much love. Not every family member was as accepting of my sexuality, which was really disappointing, but I had more than enough support from my chosen family to finally overcome the fear that I had held on to for so long. 

Travis: I realized I wasn’t completely straight at some point in high school. Growing up Catholic, I was always taught that men are attracted to women and that being gay was a sin. So when I found myself attracted to both girls and guys during high school, I wondered what was wrong with me. I brushed it off and ignored that aspect of my sexuality for a long time, which I would later come to regret since it definitely fed into ongoing anxiety and depression in college.

I first came out to my closest friends during my junior year of college. By that point, I had fully accepted that I wasn’t straight, but I had never acted on my bisexuality. I had only dated girls, so my friends saw me as completely straight. I couldn’t quite figure out how to tell them, and it ended up happening organically while hanging out on a Friday night. We were playing a game around the table that required everyone to share something no one else knew about them. Something came over me and I decided to throw caution to the wind with a, “by the way… I’m bi.”  

I came out to my parents several years later when I was working my first engineering job out of college, living in Silicon Valley and loving life. I knew that if they chose not to accept me, it was going to be their loss. After a night out (and an amazing prime rib dinner) when they were in town, I told them that there was something I wanted to tell them about myself - that I am bisexual. My dad’s first response was, “What does that mean?” I informed them that it means I am attracted to both men and women, though more recently, I’ve come to think of myself as being attracted to interesting people regardless of the gender they identify as. My parents were very supportive, but truthfully I had reached a point where I could be accepting of the worst-case scenario. 

Ben: I was most grateful for the sense of relief I experienced. Despite facing criticism and homophobia from some of my siblings after coming out, I couldn’t shake the sense of pride I felt from allowing myself to be unapologetically queer and visible. I’m finally allowing this part of me to flourish and grow. It’s liberating to be radically honest with yourself and others, regardless of what anyone else may think. I’ve now come to identify with the term queer in addition to bisexual. Part of the growth I’ve experienced involves unlearning so much of what I’ve been socialized to believe about the gender binary, and I’m just now starting to understand where I exist outside of it.  

Travis: When I came out to my friends during college, we stayed up talking until very late into the night. I left feeling a huge weight lifted off of my shoulders — and so full of love and support from some of the people I was closest to.

And later when I came out to my parents, they accepted me with open loving arms, for which I’m grateful, but I was also prepared to move forward with my life even if they did not accept me as my true authentic self.

What resources, support groups, or communities did you rely on when coming out? 

Ben: The isolation of being in the closet can sometimes lead to stories or expectations of yourself that aren’t necessarily helpful, or true. For me, as a bisexual, some of those expectations sounded like “I’m not queer enough,” “I don’t fit into the queer community,” or “people won’t believe I’m bi/queer.” I looked to my queer friends and even to LGBTQ+ advocates on social media and was relieved to find that they had many of the same fears about coming out as I did. I found that learning from other people’s experiences could help validate my own feelings, even if we had a different orientation or gender. As a queer Latinx, I also sought validation from people who shared similar intersections around my identity, which helped me navigate the concerns I had about coming out to my family.

Travis: My friends were very supportive so I was really able to lean on them. It was also helpful to just search online for other people’s coming out stories. Before I could tell my family, I knew I had to reach a point where I would be secure in my identity regardless of the outcome of that conversation. Part of the reason it’s so important to share coming out stories is because hearing other people’s experiences helps inspire you to do the same.

What advice would you give to others considering coming out? 

Ben: Above all, put your safety first. Try your best to not take on the burden of guilt for not being your authentic self — that is not a reflection of you, but a reflection of how our environment can fail to provide the validation we deserve. Take your time and build your comfort with folks who will validate your experience. There’s a whole community of people who will back you up and care for you if someone you come out to is hurtful or invalidating. 

Travis: Do it if, and when, you’re ready. You can never control how others will react, so just accept that other people’s responses have nothing to do with you. It took me years to reach that point with my family. It can be incredibly tough, and you can never know in advance how anyone will respond, but if they cannot accept you for your true authentic self, there are plenty others out there who will.

Do you have any suggestions for allies? 

Ben: I would stress the importance of familiarizing yourself with queer history and how our struggle for acceptence has evolved over the years. The LGBTQ+ community and allies have so much to be proud of today, like the repeal of “Don’t ask, don’t tell” (a former U.S. policy that directed military applicants to not disclose their sexual orientation), the legalization of gay marriage, and more queer representation on our screens — just to name a few.

At the same time, while all of those are certainly celebratory milestones, I ask that allies also recognize that our pride comes from so much more than a handful of legislative victories over the last decade. Our pride comes from the queer folks who came before us and fought for our visibility by rallying voices to speak out against injustice. Allies can research events such as the Compton’s Cafeteria riot, the Stonewall uprising, or the works of the Combahee River Collective. Understanding this historical context is important for also understanding the intersectional nature of the LGBTQ+ struggle for acceptance and restorative justice. Even though we have much to celebrate, our struggle continues as we fight for those who are still excluded or marginalized. 

Travis: Listen. The number one thing you can do is to listen and accept what someone in the LGBTQ+ community is telling you as their truth. It may change in the future — and that’s okay! Sexuality and gender are not a binary, and both can be incredibly fluid.

For parents: how you discuss sexual orientations and gender identities at home can leave a lasting impact on your children. I remember asking my mother about her thoughts on gay marriage, and she shared a more traditional view of marriage as a union between a man and a woman. That stuck with me for a long time and is a key reason I waited so long to tell them who I truly am. Read your toddler a book about a gay couple that gets married, teach your teens about prominent members of the LGBTQ+ community (and why they’re important), and if your LGBTQ+ child asks you to drive them to gay prom, treat the scenario as completely normal — because it is.

Why is it important for you to work at a company that values diversity in all forms? 

Ben: For me it’s a requirement that a company I work for prioritizes diversity and inclusion. I appreciate that Alto provides visibility into the progress that we’ve made towards building a diverse team that reflects the diversity of the patients we build solutions for. We also hold space to identify the work that still needs to be done. It’s really validating to have your background recognized at company celebrations and events or in spaces like employee resource groups (ERGs)*. It’s also important that we do all we can in our everyday actions to foster a collaborative and inclusive environment — one where people feel comfortable enough to be their authentic selves and not like they have to mask their gender, race, neurodivergence, or any other part of their identity. 

Travis: The U.S. — and the world — is made up of so many different people. There’s diversity of thought and beliefs, educational experiences, socioeconomic status, gender, race, A homogenous company that doesn’t mirror that diversity  will never be able to serve the entire population, and will miss out on a lot of opportunities. Alto’s mission is to fulfill medicine's true purpose — to improve quality of life — for everyone who needs it. The key word to me is everyone, and to truly fulfill the promise of that mission, we need a company as diverse as our customers. I personally find it rewarding to work at a company that values diversity and has strong representation of many identities, because that’s how the best ideas come to fruition and ultimately how the most positive impact is achieved.

At Alto, we believe in a world where every perspective matters. Diversity fosters creativity and creates innovation, and we welcome candidates of all backgrounds, skill sets, and experiences. To learn more, read Why We Prioritize Diversity at Alto. 

For more information on how to make your workplace safe and equitable for LGBTQ+ team members, read 11 Simple Ways You (Yes, You!) Can Make Your Workplace More LGBTQ Inclusive. 

If you or someone you know is considering coming out, we encourage you to review these resources:

Parents, Families, and Friends of Lesbians and Gays (PFLAG) Recommended Reading: Coming Out

*ERGs are meant to empower community groups within an organization by directly linking decision makers and implementing policies that support the group’s specific needs. The groups often center around a shared identity or experience and focus on building community, providing support, and contributing to its members’ personal and professional well-being. By creating an open forum for employees to come together, discuss challenges and opportunities, and foster a sense of belonging, ERGs help both individuals and organizations thrive.

The Next Evolution of Our Company Values

A lot has changed at Alto since Matt and I first set out to transform the pharmacy experience back in 2015. (For one thing, we no longer work out of a storage closet.) In the past two years alone, we’ve quadrupled our team to more than 1,000 Altoids and opened new locations in Denver, Las Vegas, Seattle, New York City, Houston, Dallas, San Jose and San Diego.

Our mission — improving the quality of life for everyone who needs medicine — will never change, but a team of 1,000 needs a different recipe for success than one of 100. And as our team continues to grow, along with our geographic footprint, we’ve revisited our core values so that we can move forward with intention and clarity during this next phase of Alto’s journey.

Here are the values that guide our work today.

This was at the top of our founding values, and it’s still here. In fact, our resolve to put patients first has only gotten stronger — not because it’s what is best for the business, but because it is our only reason for being in business. Each member of our team strives to build a world where healthcare companies truly prioritize the needs of their patients, and we’ll do everything in our power to make that a reality.

My personal favorite of all our new values, dancing in the storm is about embracing the bumps in the road — and there are many when you’re taking on challenges within healthcare — and recognizing that you can always choose joy. We strive to help our teammates do the same by infusing a little bit of levity and laughter into the workday. It only takes one person to start a dance party!

Humility is not thinking less of yourself, but thinking of yourself less. Nor is it the absence of strong opinions, but the willingness to learn and change our minds. Sometimes our ego takes over — that’s only human. But we try to be mindful of it, and willing to let go of our ego and instead put our mission, customers, and teammates ahead of ourselves.

We view ourselves as creators of our circumstances, responsible for our actions and our own well-being. When we don’t like an outcome, we don’t project blame onto others or ourselves, but rather take radical responsibility for how we created the situation. More than any other value, this is an opportunity for deep internal reflection, and by practicing it consistently, we can maximize our own individual growth.

We say what is true for us in the moment, even when it is uncomfortable. We support our teammates to do the same by recognizing the validity of their experience and not taking it personally. Leading with candor isn’t always easy, but it feels much better to live authentically and honestly and to work with others who do as well. Candor doesn't have to be angry or hurtful - it can be kind and binding, compassionate and respectful.

It’s easy to become paralyzed by fear, overwhelmed by all of the possibilities in a complex situation. So unless a decision involves customer or employee safety, we don’t wait for perfect information. We trust our intuition and common sense and simply forge ahead, knowing that mistakes are in fact one of the best ways to learn.

There are no shortcuts or silver bullets in an industry as complex as healthcare. The way to achieve transformational change is through continuous improvement over a long period of time. When we’re overwhelmed by the magnitude of what we’re trying to accomplish, we remember that what each of us does adds up — one step at a time, one customer at a time — and that with small but steady progress we can accomplish great feats.

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